The Initiative


The OBJECTIVES of the “NETWORK” include:

  • The efficient exchange of experience and information on the characterization of biomaterials utilized in biomedical applications

  • the formulation/application of novel approaches in assessing the biological properties of materials

  • the comparative assessment of the mechanical, physical and biological properties of biomaterials

The ORTHODONTIC BIOMATERIALS NETWORK was initiated by T. Eliades in 2002 as a research network of Universities and Research Centers from Greece, UK and Germany. Since 2011 it includes the Orthodontic Biomaterials Lab at the Clinic of Orthodontics and Pediatric Dentistry of the University of Zurich, the Department of Biomaterials at the School Dentistry, University of Athens, the Experimental Orthodontics Laboratory at the University of Bonn, Germany, the Adhesive Biomaterials and Biomechanics / Biomaterials Science Research Group at the University of Manchester, UK and the Institute of Biosciences & Applications, Laboratory of Cell Proliferation & Ageing, NCSR “Demokritos”.

The Laboratories

University of Zurich

Center of Dental Medicine, Clinic of Orthodontics and Pediatric Dentistry, Orthodontic Biomaterials Lab

University of Manchester

Dental School, Adhesive Biomaterials and Biomechanics / Biomaterials Science Research Group

NCSR «Demokritos»

Institute of Biosciences & Applications, Laboratory of Cell Proliferation & Ageing

The People

Theodore Eliades
Theodore EliadesProfessor and Director
Clinic of Orthodontics and Pediatric Dentistry, Center of Dental Medicine, Faculty of Medicine, University of Zurich, Switzerland
Spiros Zinelis
Spiros ZinelisProfessor
Department of Biomaterials, School of Dentistry, National and Kapodistrian University of Athens, Greece
Christoph Bourauel
Christoph BourauelProfessor and Head
Endowed Chair of Oral Technology, School of Dentistry, University of Bonn, Germany
Nick Silikas
Nick SilikasProfessor
Dental Biomaterials Science, Faculty of Biology, Medicine and Health, University of Manchester, UK
Dimitris Kletsas
Dimitris KletsasResearch Director
Laboratory of Cell Proliferation and Ageing, Institute of Biosciences and Applications, NCSR “Demokritos”, Greece
Christos Cholevas
Christos CholevasResearcher
Department of Pharmaceutical Technology ,School of Pharmacy, Faculty of health Sciences, AUTH, Greece


The services provided by ORTHODONTIC BIOMATERIALS NETWORK include:

  • Performing biological assays and mechanical-physical tests for commercially available materials.

  • Developing appropriate techniques for quality control and characterization of biomaterials.

  • Elucidating the mechanisms and mediation of acute and long term cytotoxicity for polymeric and metallic biomaterials.

  • Assessing the corrosion potential of biomaterials.

  • Biomechanical testing and theoretical modeling of anatomical structures.


Surface characterization of biomaterials


Clinical trials of materials’ performance


Orthodontically-induced enamel alterations


Biological properties of materials


Research on orthodontic alloys




Tissue Mechanics


Properties of orthodontic polymers


Retrieval analysis: the inappropriateness of in vitro testing protocols